«M.Sc., DEGREE [Choice Based Credit System (CBCS)] Branch IV (A) CHEMISTRY (Specializations in Organic, Inorganic and Physical Chemistry) REGULATIONS ...»
Raman spectroscopy – Theory, instrumentation – source of radiation and detectors; few qualitative and quantitative applications; Resonance Raman spectroscopy.
UNIT III Nuclear Magnetic Resonance and Electron Spin ResonanceSpectroscopy
Nuclear Magnetic Resonance Spectroscopy –Theory, relaxation and saturation processes, Environmental effects; instrumentation - type of magnets, source, detector and sample handling; few application of proton NMR; qualitative and quantitative analysis.
Electron Spin Resonance –Theory, instrumentation and a few applications in qualitative and quantitative analyses.
UNIT IV Polarography and Amperometry
Polarography – Theory, apparatus, DME, diffusion kinetic catalytic currents, current voltage curves for reversible and irreversible system, qualitative and quantitative application to inorganic systems.
Amperometric titrations – Theory, apparatus, types of titration curves, successive titrations and two indicator electrodes-applications.
UNIT V Chromatography Gas liquid chromatography-principle, retention time values, instrumentation, carrier gas, column, detectors- thermal conductivity, flame ionization and electron capture; few applications of GLC.
1. Willard, Merit, Dean and Settle, Instrumental Methods of Analysis, CBS Publishers and Distributors, IV Edn. 1986
2. Schoog, Holler, Nieman, Principles of Instrumental Analysis, Thomson Asia Pte Ltd., Singapore, 2004.
3. D.A. Skoog, Principles of Instrumental Analysis, Saunders College Pub.Co, III Edn., 1985
4. A.I Vogel, Text Book of Quantitative Inorganic Analysis, ELBS III Edn, 1987.
5. J.O.M. Bockris and AKN Reddy, Modern Electrochemistry, Plenum, 1970.
6. D.A.Skoog and D.M.West Fundamentals of Analytical Chemistry, Holt Rinehart and Winston Publications, IV Edn, 2004.
7. W. Kemp, NMR in Chemistry, MacMillan Ltd,1986.
1. Albert Paul Malvino Electronic Principles, PMH Publishers, III Edn, 1984.
2. J.G. Dick, Analytical Chemistry, McGraw Hill Publishers, 1974.
3. G.W.Ewing, Instrumental Methods of Chemical Analysis, McGraw Hill Pub, 1975.
4. B. H. Vassos and G.W. Ewing, Electroanalytical Chemistry, John Wiley and Sons, NY, 1983
5. R. Greef, R. Peat, L.M. Peter, D. Pletcher and J. Robinson, Instrumental methods in Electrochemistry, Ellis Horwood, Chichester, 1985.
6. A.J. Bard and L.R.Faulkner, Electrochemical methods; Fundamentals and applications, J. Wiley and Sons, NY, 1980.
CHE E03 ENVIRONMENTAL CHEMISTRYHours L T P C UNIT I Fundamentals Fundamentals of Environmental Chemistry- Chemical potential, chemical equilibria, acid base reactions and carbonate system, sampling techniques for air, water, and soil.
UNIT II Water Chemistry Water chemistry- properties of water, nature of metal ions in water, solubility of gases in water, occurrence of chelating agents in water; Redox potential, Significance of redox equilibiria in natural and waste water; microorganisms; The catalyst of aquatic chemical reactions, water pollution and its effects, eutrophication concept of DO, BOD, COD, Sedimentation. Coagulation and filtration.
UNIT III Atmospheric Chemistry Atmosphere- Nature and composition of atmosphere, chemical and photochemical, reactions in the atmosphere – OZONE and PAN ions and radicals in the atmosphere; gaseous organic and inorganic pollutions in the atmosphere; Global warming and effects of CO, SO2, NOx.
UNIT IV Soil Chemistry Soil chemistry- inorganic and organic components of soil, Nitrogen pathways. NPK in soils; Toxic chemicals in the environment pesticides and their toxicity; biochemical aspects of arsenic, cadmium, lead & mercury.
Environmental chemistry of hazardous wastes, hazardous wastes in hydrosphere, geosphere and atmosphere, industrial production of hazardous wastes; Health effects of hazardous wastes.
1. Sharma and Kaur, Environmental Chemistry, Krishna Publishers, New Delhi, 2000.
2. A.K. De, Environmental Chemistry, Wiley Eastern Ltd, New Delhi, 1989.
1. J.Rose Gordon and Breach (Ed.), Environmental Toxicology, Science Publication, New York, 1993.
2. S.Ladsberger and Creatchman (Ed.), Elemental Analysis of Airborne Particles, Gordon and Breach Science Publication New York, 1998.
3. S.E Manahan, Environmental Chemistry, Lewis Publishers, London, 2001.
4. S.M. Khopkar, Environmental Pollution analysis, Wiley Eastern, New Delhi, 1994.
5. S.K. Banerji, Environmental Chemistry, Prentice Hall of India, New Delhi, 2003.
CHE E04 POLYMER CHEMISTRYHours L T P C
UNIT I Basic Concepts
Basic concepts: Monomers, repeat units degree of polymerization, linear, branched and network polymers. Condensation polymerization: Mechanism of stepwise polymerization. Kinetics and statistics of linear stepwise polymerization. Addition polymerization: Free radicals, cationic and anionic polymerization. Polymerization conditions. Polymerization in homogeneous and heterogeneous systems.
UNIT II Coordination and Copolymers Coordination Polymerization: Kinetics, mono and bimetallic mechanism of copolymers. Copolymerization: Block and graft copolymers, kinetics of copolymerization.
Evaluation of monomer. Reactivity ratio. Rate of copolymerization.
UNIT III Molecular Weight Molecular weight and properties of polymers; Polydispersion-average molecular weight concept, number weight and viscosity average molecular weights. Measurement of molecular weights. Gel permeation chromatography, viscosity, light scattering, osmotic and ultracentrifugation methods. Polymer structure and physical properties –crystalline melting point Tm. The glass transition temperature. Determination of Tg. Relationship between Tm and Tg.
UNIT IV Processing
Polymer Processing: Plastics elastomers and fibres. Compounding processing techniques: calendaring, die casting, rotational casting, film casting, injection moulding, blow moulding extrusion moulding, thermoforming, foaming, reinforcing and fibre spinning.
UNIT V Commercial Polymers Properties of Commercial Polymers: Polyethylene, polyvinyl chloride, polyamides, polyesters, phenolic resins, epoxy resins and silicone polymers. Functional polymers-Fire retarding polymers and electrically conducting polymers. Biomedical polymers- contact lens, dental polymers, artificial heart, kidney, skin and blood cells.
Text Books F.W.Billmeyer, Text Book of Polymer Science, 3rd Edn., John Wiley & Sons, 1.
New York, 2003.
2. V.R.Gowarker, N.V.Viswanathan and J. Sreedhar, Polymer Science, New Age International, New Delhi, 2003.
UNIT I Structure and properties of metals and alloys Crystal structure of metals and alloys, intermetallic compounds, interstitial compounds, electronic compounds; electrical and magnetic properties of metals-resistivity, magnetoresistance, de Hass Van Alphen effect, cyclotron resonance, hall effect, thermoelectric power, superconductivity, diamagnetism, ferromagnetism, anti-ferromagnetism, Pauli paramagnetism, Einstein de Hass effect, magnetic resonance spectroscopy.
UNIT II Solid Electrolytes, Semiconductors and Super Conductors
Semiconductors- properties, semiconductor and metal electrodes, semiconductor-electrolyte interface, semiconductor – electrolyte junction, space charge layer, depletion layer, Helmholtz and Gouy layer and flat band potential; Solid electrolytes – Ag+ conductors, Li+ conductors, Cu+ conductors, F- conductors, O22conductors, beta-alumina and other conductors; applications of solid electrolytes; super conductors-super conducting materials and compounds, magnetic properties, heat capacity, energy gap, MW and IR properties, super conducting magnets, high Tc superconductors; characterization.
UNIT III Photoconductors, Photovoltaics, Solar Cells and Solar Coatings Photocells-photoemissive, photo conductive and photovoltaic cells; photo conductive effect, photo current, photo conductivity, speed of response, photosensitivity, preparation of photoconductors and photovoltaic effect; photoelectrochemical cells, photoelectrolytic cells; Applications. Solar coatings-solar foils, black chrome, black nickel, black alumina, black zinc, black copper, blackened steel, blackened SS and black cobalt.
UNIT IV Oxide Films, Thin Films and Membranes Growth of oxide films-barrier oxide layer, composition, structure and physical properties; Thin films-various stages of film growth, defects during growth, grain boundaries, surface area and roughness; techniques of film growth- PVD, CVD, CSVT, sputtering and plasma deposition. Membranes-types of diaphragm and membrane materials; Preparation of membranes-physical methods, Leach or Cook out method, gelatin process; Applications
UNIT V Luminescent Materials and Conducting Polymers
Luminescence - photoluminescence, electroluminescence and cathadoluminescence; Fluorescent phosphors-Calcium tungstate phosphor, Zinc silicate green phosphor, Magnesium fluogermanate red phosphor and Calcium halophosphate day light phosphor Conducting polymers-intrinsically conducting polymers, extrinsically conducting polymers, non-bridged polymers and chain bridged polymers; Synthetic methods;
methods of doping-simple chemical doping, electrochemical doping and photochemical doping.
1. V.A. Myamlin and Y.V. Pleskov, Electrochemistry of semiconductors, Plenum press, New York, 1979.
2. J.M.Blatt, Theory of super conductivity, Academic press, 1964.
3. K.L. Chopra, Thin films, Mc.Graw Hill Book Co.,1982.
V.Ragavan, Materials Science and Engineering, First Course, 2nd Edn., 4.
Prentice-Hall India, 1985.
5. N. Cusack, Electrical and magnetic properties of solids, Langmans, 1958.
1. E.C.Subba Rao, Solid electrolytes and their applications, Plenum Press, 1980.
2. H.J. Hovel, Semiconductors and semiconducting materials Vol.2. Solar cells, Academic press, 1975.
3. R.H. Bube, Photoconductivity of solar cells, John Wiley & sons. Inc.,1967.
4. D. Curie, Luminescence in crystals, John Wiley & Sons, Inc., New York, 1963.
5. A.Skothem (Ed.), Hand book of conducting polymers – Vol. I and II, Marcel Dekkar, 1986.
CHE E06 MEDICINAL CHEMISTRYHours L T P C Unit I Basic Concepts Drug design - analogues and pro-drugs, factors governing drug design, rational approach,method of variation and tailoring of drugs; Physical properties-factors governing drug action at active site, factors governing ability of drugs to reach active site, dissociation constants, isosterism and bioisosterism; general anaesthetics-inhalation anaesthetics, intravenous anaesthetics and basal anaesthetics;mode of action; local anaesthetics-classification and syntheses, sedatives and hypnotics-classification, synthesis, mode of action and structure-activity relationship.
Unit II Anticonvulsants, Stimulants and Antipyretic Analgesics Anticonvulsants - classification, synthesis and mode of action; Muscle relaxants-classification, synthesis and mode of action. Central nervous system stimulants- classification, synthesis and mode of action; Antipyretic analgesicsclassification, synthesis and mode of action;
Unit III Other Analgesics Narcotic or Opiate analgesics - classification, preparation and mode of action;
Narcotic antagonists; Cardiovascular drugs-classification, synthesis and mode of action;
Autonomic drugs-synthesis and mode of action of sympathomimetic drugs, antiadrenergic drugs, cholinomimetic drugs, antimuscarinic drugs, ganglionic blocking agents and adrenergic neurone blocking agents; Diuretics - synthesis and mode of action of mercurial and non-mercurial diuretics.
Unit IV Antihistamines, Anti-inflammatory and Antiparkinson drugs Antihistaminics - synthesis and mode of action of histamine H1 receptor antagonists and histamine H2-receptor blockers; prevention of histamine release;
structure-activity relationships amongst H1-receptor blockers. Non-steroidal anti-inflammatory drugs(NSAID)-synthesis and mode of action of heteroarylacetic acid analogues, arylacetic acid analogues, arylpropionic acid analogues, naphthalene acetic acid analogues, gold compounds, salicylic acid analogues and pyrazolones and pyrazolodiones; Antiparkinsonism agents-synthesis and mode of action of piperidine analogues, pyrolidine analogues and phenothiazine analogues.
Unit V Other drugs Expectorants and antitussives-synthesis and mode of action of sedative expectorants, stimulant expectorants and centrally acting antitussive agents.
Sulphonamides-preparation and mode of action of sulphonamides for general, urinary, intestinal and local infection; sulphonamide inhibition. Antimalarials-synthesis and mode of action of aminoquinoline analogues, aminoacridine analogues, guanidine analogues, pyrimidine analogues, sulfone and quinine analogues; Steroids-synthesis and mode of action of sterols, sex harmones, cardiac glycosides, bile acids and sapogenins.
Antibiotics-synthesis and mode of action of penicillins, aminoglycoside antibiotics, chloramphenicol and tetracyclines.
1. Ashutosh Kar, Medicinal Chemistry, New Age International, 1996.
2. W.O.Foye, Principles of medicinal chemistry, 2nd edn., Lea & Febiger, Philadelphia, 1981.
Unit I Introduction Colour and chemical constitution - chromophore, auxochrome and resonance, various theories; History of natural and synthetic dyes; Names of commercial dyes; Study of raw materials and dyestuff intermediates; Unit operations - nitration, sulphonation, halogenation, amination, diazotisation and alkali fusion; Colour index and its significance;
Classification of dyes based on chemical constitution and method of applications;
General properties - linearity, coplanarity and fastness.