«M.Sc., DEGREE [Choice Based Credit System (CBCS)] Branch IV (A) CHEMISTRY (Specializations in Organic, Inorganic and Physical Chemistry) REGULATIONS ...»
SALEM – 636 011
[Choice Based Credit System (CBCS)]
Branch IV (A) CHEMISTRY
(Specializations in Organic, Inorganic and Physical Chemistry)
REGULATIONS AND SYLLABUS
[ For the Candidates admitted from the academic year
2009 – 2010 and onwards ]
Objectives of the Course I.
Eligibility for Admission II.
Duration of the Course III.
Course of Study IV.
Teaching Methodologies V.
Scheme of Examinations VII.
Question Paper Pattern VIII.
Distribution of marks for practical examination IX.
Dissertation / Project Work X.
Rural Development Course (RDC) XI.
Passing minimum XII.
Classification of successful Candidates XIII.
XIV. Maximum Duration for the Completion of the Course Commencement of this Regulation XV.
XVI. Transitory Provision XVII. Syllabus XVIII. Model Question Papers XIX. List of Question Paper setters / Examiners I. Objectives of the Course Life has changed more in the past two centuries than in all the previously recorded span of human history. In one-way or another, all the changes involve CHEMISTRY.
Chemistry is central to the current revolutions in Science. No educated person today can understand the modern world without a basic knowledge of chemistry. The existence of a large number of chemical factories, mines and related industries in the catchments of University necessitates chemistry education. Hence our goal in introducing the M.Sc programme in Chemistry with three specializations has been to educate the undergraduate students in the fascinating fields of chemistry in an effective manner.
Rigorous and comprehensive in approach, this syllabus presents essential contents in a detailed, clear and direct way.
M.Sc. Chemistry with specializations in Organic Chemistry, Inorganic Chemistry and Physical Chemistry is a unique kind of course dealing with all aspects of chemistry such as preparation, properties, structure elucidation, kinetics and mechanism of the reaction, techniques of analysis for different kinds of materials, which are very
essential for the human society. The major objectives of M.Sc. Chemistry course are:
To impart knowledge in fundamental aspects of all branches of chemistry (Organic • chemistry, Inorganic Chemistry and Physical Chemistry).
To acquire deep knowledge in the study of physical, chemical, electrochemical and • magnetic properties, structure elucidation using various techniques and applications of various organic and inorganic materials and To acquire basic knowledge in the specialized areas like Polymer chemistry, • Environmental Chemistry, Dye Chemistry, Pharmaceutical Chemistry etc.
This programme is offered under Choice Based Credit System (CBCS). The CBCS enables the students to select variety subjects as per his interest and requirement.
Acquiring knowledge in the related fields is advantageous to the students. Fast learners can earn more credits than the stipulated minimum of 72 credits. The programme is structured in such a way to impart more knowledge in science, in particular in Chemistry.
Eligibility for Admission II.
A candidate who has passed B.Sc., Degree Examination with Branch IV Chemistry as main subject of study of this university or any of the B.Sc., degree examination with specialization such as Industrial chemistry, Polymer Chemistry, Applied Chemistry, Pharmaceutical Chemistry or any other specialization in Chemistry of some other university accepted by the syndicate as equivalent thereto, subject to such condition as may be prescribed therefore shall be permitted to appear and qualify for the M.Sc. degree in Chemistry with specializations in Organic, Inorganic and Physical Chemistry of this University after a course of study of two academic years.
V. Teaching Methodologies The classroom teaching would be through conventional lectures and use of OHP and Power Point presentations. The lecture would be such that the student should participate actively in the discussion. Student seminars would be conducted and scientific discussions would be arranged to improve their communicative skill.
In the laboratory, instruction would be given for the experiments followed by demonstration and finally the students have to do the experiments individually.
Periodic tests would be conducted and for the students of slow learners would be given special attention.
Total 200 marks _________ (a) Topic:
The topic of the dissertation shall be assigned to the candidate before the end of first semester and a copy of the same should be submitted to the University for Approval.
(b) Advisory Committee:
Each guide shall have a maximum of five students.
There will be an advisory committee consisting of the guide as chairman and one member from the same department or allied departments of the University.
(c) Plan of Work:
The student should prepare plan of work for the dissertation, get the approval of the advisory committee and should be submitted to the university during the second semester of their study. In case the student want to avail the facility from other University/laboratory, they will undertake the work with the permission of the guide and acknowledge the alien facilities utilized by them.
The duration of the dissertation research shall be a minimum of three months in the fourth semester.
(d) Dissertation Work out side the Department:
In case the student stays away for work from the Department for more than one month, specific approval of the university should be obtained.
(e) No.of copies/distribution of dissertation:
The students should prepare three copies of dissertation and submit the same for the evaluation by Examiners. After evaluation one copy is to be retained in the Department library and one copy is to be submitted to the University (Registrar) and one copy can be held by the student.
XI. Rural Development Course (RDC) The four districts in the jurisdiction of Periyar University are very backward districts, where a majority of the people lives in poverty. The rural mass is economically and educationally backward. Thus the aim of the introduction of this Rural Development Course (RDC) is to extend outreach programs in environmental awareness, hygiene and health to the rural masses of this region.
The students in their Third semester have to visit any one of the villages within the jurisdiction of Periyar University and can arrange various programmes to educate the rural masses in the following areas for three days. A minimum of two faculty members can accompany the students and guide them.
1. Environmental awareness
2. Hygiene and health This course is a compulsory course for all the M.Sc Chemistry students of the Department of Chemistry, Periyar University. Students will be awarded TWO credits apart from the minimum credits 90 to be earned for the M.Sc. programme.
XII. Passing Minimum The candidate shall be declared to have passed the examination if the candidate secures a minimum of 50 % (Each in Internal and External) in the University examination.
For a pass in the Practical paper, a candidate has to secure a minimum of 50% marks in the University examination. There is no passing minimum for the record notebook. However submission of a record notebook is a must.
For the project work and viva-voce a candidate should secure 50% of the marks for pass. The candidate should compulsorily attend viva-voce examination to secure pass in that paper.
Candidates who do not obtain the required minimum marks for a pass in a paper/Project Report shall be required to appear and pass the same at a subsequent appearance.
XIII. Classification of Successful Candidates
Candidates who secure not less than 60% of the aggregate marks in the whole examination shall be declared to have passed the examination in First Class.
All other successful candidates shall be declared to have passed in the Second Class.
Candidates who obtain 75% of the marks in the aggregate shall be deemed to have passed the examination in First Class with Distinction provided they pass all the examinations prescribed for the course at the first appearance.
Candidates who pass all the examinations prescribed for the course in the first instance and within a period two academic years from the year of admission to the course only are eligible for University Ranking.
A candidate is deemed to have secured first rank provided he/she (i) should have passed all the papers in first attempt itself (ii) should have secured the highest over all grade point average (OGPA) XIV. Maximum Duration for the Completion of the Course The maximum duration for completion of M.Sc. Degree in Chemistry with specialization Organic/Inorganic/Physical Chemistry Programme shall not exceed eight semesters.
XV. Commencement of this Regulation These regulations shall take effect from the academic year 2009-10.i.e., for students who are to be admitted to the first year of the course during the academic year 2009-10 and thereafter.
XVI. Transitory Provision Candidates who were admitted to the M.Sc. Degree in Chemistry with specialization Organic/Inorganic/Physical Chemistry course of study before 2009-2010 shall be permitted to appear for the examinations under those regulations for a period of three years i.e., up to and inclusive of the examination of April/May 2012. Thereafter, they will be permitted to appear for the examination only under the regulations then in force.
XVII. Syllabus Core Courses
CHE C01 ORGANIC CHEMISTRY – REACTION MECHANISMHours L T P C UNIT – I Basic Concepts Formation, stability and reactions of carbenes and nitrenes. Non-classical carbonium ions.
Kinetic and thermodynamic control of chemical reactions; Methods of determining reaction mechanism - kinetic methods – Primary and secondary kinetic isotopic effects;
Non-kinetic methods – Study of intermediates, product analysis, isotope labeling, Stereochemical studies and cross over experiments; Principle of microscopic reversibility; Hammond postulate.
Linear free energy relationship; Hammett equation – Significance of reaction and substituent constants ( and ); Taft equation.
UNIT II Substitution Reactions Mechanism of aliphatic nucleophilic substitution - SN1, SN2, SN1CB and SNi mechanisms, Ambient nucleophiles, Neighbouring group participation, Nucleophilic substitution at allylic and vinylic carbon. Mechanism of aliphatic electrophilic substitution SE1, SE2 mechanisms – Simple examples.
Concept of aromaticity; Nonaromatic and antiaromatic systems; Craig’s rule;
Alternant and non-alternant hydrocarbons; Chemistry of fullerenes, annulenes and heteroannulenes.
Mechanism of aromatic electrophilic substitution - and complexes, nitration, halogenation, sulphonation, Friedel–Crafts alkylation and acylation, Reimer-Tiemann reaction and Gattermann – Koch formylation; Orientation and reactivity.
Mechanism of aromatic nucleophilic substitution - benzyne mechanisms.
UNIT III Elimination Reactions E1, E2, E1cB and E2C mechanisms; Stereochemistry of elimination – Hofmann and Zaitsev rules; Competition between elimination and substitution; pyrolytic cis elimination – Chugaev reaction; Bredt’s rule; Hofmann degradation and Cope elimination.
UNIT IV Addition Reactions Electrophilic, Nucleophilic and Free radical additions – Additions of halogen and halogen acids to C–C multiple bonds; Markovnikov and Anti Markovnikov addition;
Stereochemistry of additions; Hydroboration and Diels – Alder reactions.
Reactions of carbonyl group – Mechanisms of Aldol, Perkin, Stobbe and Dieckmann condensations; Conjugate additions to, – Unsaturated carbonyl and nitrile systems – Michael addition.
UNIT V Alkaloids and Terpenoids General methods of structure elucidation of alkaloids; Structure, synthesis and stereochemistry of the following alkaloids – Quinine, papaverin, lysergic acid, atropine and reserpine; Biosynthesis of alkaloids.
Structure, Stereochemistry and synthesis of zingiberene, cadinene and abietic acid; Biosynthesis of terpenoids.
1. Jerry March, Advanced Organic Chemistry – Reactions, Mechanisms and Structure, IV Edn., John Wiley & Sons, 1992.
2. P.Sykes, A Guide Book to Mechanisms in Organic Chemistry, VI Edn., Longmans Scientifics and Technical, Essex 1986.
3. S.M. Mukherji and S.P.Singh, Reaction Mechanism in Organic Chemistry, III Edn., MacMillan, 1984.
4. I.L. Finar, Organic Chemistry, Vol. II, V Edn. First Indian reprint, Pearson Education Asia Pvt. Ltd. 2000.
1. F.A.Carey and Sundberg, Advanced Organic Chemistry, Part A & B, III Edn.
Plenum Press, 1990.
2. S.H.Pine, J.B. Hendrickson, D.J.Cram and G.S.Hammond, Organic Chemistry, IV Edn. McGraw-Hill Company 1980.
3. T.H. Lowry and K.S. Richardson, Mechanism and Theory in Organic Chemistry, Harper and Row, NY 1976.
4. P.S.Kalsi, Organic Reactions and Mechanisms, II Edn. New Age International Publishers, 2000.
5. J.M.Harris and C.C. Wamser, Fundamentals of Organic Reaction Mechanisms, John Wiley & Sons, Inc. 1976.
6. R.K. Bansel, Organic Reaction Mechanisms, Tata McGraw Hill, 1975.
7. S.W. Pelletier, Chemistry of Alkaloids, Van Nostrand Reinhold, 1970.
8. A.A.Newman (Ed.), Chemistry of Terpenes and Terpenoids, Academic Press, London, 1972.
9. P.Mehta and M.Mehta, Organic Chemistry, Prentice Hall India, New Delhi, 2005.
CHE C02 ORGANIC PHOTOCHEMISTRY AND PERICYCLIC REACTIONS
UNIT I Stereochemistry and Conformational Analysis Newman, Sawhorse and Fisher projection formulae and interconversions;